Mitotic and Meiotic Cell Cycle control and executions

Roscoff (Bretagne), France, April 8-12, 2019

Deadline for application : January 21, 2019

Chairperson: Iain Hagan

CRUK Manchester Research Institute, University of Manchester, Alderley Park, SK10 4TG, United Kingdom
Phone: +44 7530284701
Email: Iain.Hagan@manchester.ac.uk

Vice-chairperson: Katja Wassmann

Sorbonne Université, IBPS, UMR7622 CNRS, 7 quai St. Bernard case 24, 75252 Paris Cedex 05, France
Phone: +33 (0)1 44 27 33 01
Email: katja.wassmann@upmc.fr

The accurate, appropriate and timely control and execution of cell division regulates virtually every aspect of biology from proliferation through development to disease.  Universal as cell division is, there is great variation in the contexts, rates and topology within which the cell cycle is triggered and executed. Each distinct circumstance, be it an isolated cell in a unique nutrient environment or, a particular cell in a particular tissue, imposes distinct demands upon the core cell cycle control and genome segregation machinery. Cell division control and execution must therefore be remodelled to suit a spectrum of contexts, niches, or the more radical demands to reduce, or eliminate, the genome compliment.  While repeated rounds of symmetrical division maybe favoured by some cell types, many stem cells maintain stemness through asymmetrical division, germ cells pursue reductional divisions and cancer cells often appear to ignore the rule book and divide however they possibly can.  Insight into such diversity and control continues to reveal how much more there is to learn about cell and nuclear division.  The Conferences Jacques Monod meetings on the Cell Cycle provide a unique forum for discussing and debating these principles and the latest revelations in the field.  The next meeting in this series will be no exception. A stellar line up of international speakers will be describe their research at the cutting edge of the cell cycle and division fields to set the scene for engaging debates in the beautiful setting of the CNRS Roscoff Marine Research Station.  The intimate scale of these meetings (115 attendees in total), means that, in the likely scenario of over-subscription, the organisers may approach the heads of labs from whom multiple applications have been received to select one candidate for attendance.

Invited speakers
(provisional titles)

Renata Basto (Institut Curie, Paris, France)
The centrosome in cell division in vivo

Anna Castro (CRBM, Montpellier, France)
Do Arpp19 and ENSA play differential roles on the control of the cell cycle?

Jennifer DeLuca (Colorado State University, Fort Collins, USA)
Regulation of kinetochore-microtubule attachments throughout mitotic progression

Arshad Desai (University of California, San Diego, USA)
Co-ordinating cell division

Hironori Funabiki (The Rockefeller University, New York, USA)
Cell death in mitosis

Monica Gotta (University of Geneva, Switzerland)
Plk1 regulation in cell division and development

Iain Hagan (CRUK Manchester Institute, United Kingdom)
Cell Cycle control from the spindle pole

Jean-Paul Javerzat (Institut de Biochimie et Génétique Cellulaires, Bordeaux, France)
Protein Phosphatase 4 and the Pef1 CDK oppose each other to control cohesin binding to fission yeast chromosomes

Susanne Lens (UMC Utrecht, Netherlands)
Chromosome passenger protein complex in genome segregation

Adele Marston (Wellcome Centre for Cell Biology, University of Edinburgh, United Kingdom)
Controlling progression through meiosis

Thomas Mayer (University of Konstanz, Germany)
Protein phosphatases and their role in cell cycle progression

Sarah McClelland (Barts Cancer Institute, Queen Mary University of London, United Kingdom)
Creating Designer Karyotypes to Identify Vulnerabilities of Aneuploid Cancer

Raphaël Mercier (INRA Centre de Versailles-Grignon, France)
Control of the metaphase to anaphase transition

Tobias Meyer (Stanford University Medical Center, Stanford, USA)
The Restriction Point and cell cycle entry

David Morgan (University of California, San Francisco, USA)
Biochemical mechanisms in the control of chromosome segregation

Andrea Musacchio (Max Planck Institute, Dortmund, Germany)
Cell cycle regulation of CENP-A deposition

Kim Nasmyth (University of Oxford, United Kingdom)
Chromosome cohesion and segregation

Jakob Nilsson (University of Copenhagen, Denmark)
Regulation of cell division by protein phosphatases

Gislene Pereira (Ruprecht Karls Universitat, Heidelberg, Germany)
Spatial co-ordination of cell cycle progression

Simonetta Piatti (Centre de Recherche en Biochimie Macromoléculaire, Montpellier, France)
Controlling septin organisation for cytokinesis in budding yeast

Jonathan Pines (Institute of Cancer Research, London, United Kingdom)
Cyclin B1 and the Spindle Assembly Checkpoint: a 12 year Odyssey

Lionel Pintard (Institut Jacques Monod, Paris, France)
Cullin ring ubitquitin ligases in cell division

Suzana Storchova (Max Planck Institute, Martinsried, Germany)
Cell cycle deregulation in response to aneuploidy

Stephen Taylor (Manchester Cancer Research Centre, University of Manchester, UK)
Mitosis, genome stability and cancer chemotherapy

Marie-Emilie Terret (Centre Interdisciplinaire de Recherche en Biologie, Paris, France)
Aberrant too low cortical tension generates chromosome misalignment in mouse oocytes

Sylvie Tournier (Center for Integrative Biology, Toulouse, France)
Chromosome segregation in fission yeast: from centromeres to telomeres

Katja Wassmann (IBPS, Sorbonne Université, Paris, France)
How oocytes try to get it right: Control mechanisms that govern the meiotic divisions

Hongtao Yu (Howard Hughes Medical Institute, University of Texas Southwestern Medical Center, USA)
Microtubule-dependent rewiring of spindle checkpoint signaling

Deadline for application : January 21, 2019

Registration fee (including board and lodging)

550 € for PhD students
650 € for other participants

Application for registration
The total number of participants is limited to 115 and all participants are expected to attend for the whole duration of the conference. Selection is made on the basis of the affinity of potential participants with the topics of the conference. Scientists and PhD Students interested in the meeting should deposit online before the deadline: https://cjm1-2019.sciencesconf.org/

- their curriculum vitae
- the list of their main publications for the 3 last years
- the abstract of their presentation:

The abstract must respect the following template: TemplateResumeFile
- First line: title
- Second line: list of authors. Presenting author underlined
- Third line: author's addresses
- Fourth line: e-mail of the presenting author
Abstracts should be no longer than an A4 page and preferably be submitted in Times New Roman, font size 10 pts. No figures. ".docx" file format.

After the deadline, the organizers will select the participants. Except in some particular cases approved by the Chairperson, it is recommended that all selected participants present their work during the conference, either in poster form or by a brief in- session talk. The organizers choose the form in which the presentations are made. No payment will be sent with application. Information on how and when to pay will be mailed in due time to those selected.